BDBM206115 US9255110, 28

SMILES: CC(O)CCOc1cc2ncccc2cc1NC(=O)c1csc2cncnc12

InChI Key: InChIKey=RNCFOMCKQSBXAQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM206115 (US9255110, 28) Show SMILES CC(O)CCOc1cc2ncccc2cc1NC(=O)c1csc2cncnc12 Show InChI InChI=1S/C20H18N4O3S/c1-12(25)4-6-27-17-8-15-13(3-2-5-22-15)7-16(17)24-20(26)14-10-28-18-9-21-11-23-19(14)18/h2-3,5,7-12,25H,4,6H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC. US Patent					Assay Description Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...				US Patent US9255110 (2016) BindingDB Entry DOI: 10.7270/Q2XG9PZ2
					More data for this Ligand-Target Pair