BDBM207500 US9260439, 384

SMILES: C[C@@]1(CCN(C1)C(=O)[C@@]1(F)CCNC1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key: InChIKey=SCBXWFXUIJADDY-BJKOFHAPSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110alpha-iSH2 p85alpha Complex (Homo sapiens (Human))	BDBM207500 (US9260439, 384) Show SMILES C[C@@]1(CCN(C1)C(=O)[C@@]1(F)CCNC1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1 Show InChI InChI=1S/C24H32FN9O2/c1-23(4-7-33(15-23)20(35)24(25)3-5-27-14-24)34-6-2-17-18(16-12-28-21(26)29-13-16)30-22(31-19(17)34)32-8-10-36-11-9-32/h12-13,27H,2-11,14-15H2,1H3,(H2,26,28,29)/t23-,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.0180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
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