BDBM207650 US9265734, R130

SMILES: Nc1ccc(cc1NC(=O)CCCCCCNC(=O)c1cccnc1)-c1cccs1

InChI Key: InChIKey=SJZHMOSPHZERBV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM207650 (US9265734, R130) Show SMILES Nc1ccc(cc1NC(=O)CCCCCCNC(=O)c1cccnc1)-c1cccs1 Show InChI InChI=1S/C23H26N4O2S/c24-19-11-10-17(21-8-6-14-30-21)15-20(19)27-22(28)9-3-1-2-4-13-26-23(29)18-7-5-12-25-16-18/h5-8,10-12,14-16H,1-4,9,13,24H2,(H,26,29)(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BIOMARIN PHARMACEUTICAL INC. US Patent					Assay Description HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...				US Patent US9265734 (2016) BindingDB Entry DOI: 10.7270/Q2BK1B5B
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM207650 (US9265734, R130) Show SMILES Nc1ccc(cc1NC(=O)CCCCCCNC(=O)c1cccnc1)-c1cccs1 Show InChI InChI=1S/C23H26N4O2S/c24-19-11-10-17(21-8-6-14-30-21)15-20(19)27-22(28)9-3-1-2-4-13-26-23(29)18-7-5-12-25-16-18/h5-8,10-12,14-16H,1-4,9,13,24H2,(H,26,29)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
BIOMARIN PHARMACEUTICAL INC. US Patent					Assay Description HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...				US Patent US9265734 (2016) BindingDB Entry DOI: 10.7270/Q2BK1B5B
					More data for this Ligand-Target Pair