BDBM207746 US9265734, R26

SMILES: Nc1ccccc1NC(=O)CCCCCNC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=TVTJCIOUBKLDKF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207746   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM207746 (US9265734, R26) Show SMILES Nc1ccccc1NC(=O)CCCCCNC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C21H23ClN4O2/c22-15-9-10-17-14(12-15)13-19(25-17)21(28)24-11-5-1-2-8-20(27)26-18-7-4-3-6-16(18)23/h3-4,6-7,9-10,12-13,25H,1-2,5,8,11,23H2,(H,24,28)(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
BIOMARIN PHARMACEUTICAL INC. US Patent					Assay Description HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...				US Patent US9265734 (2016) BindingDB Entry DOI: 10.7270/Q2BK1B5B
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM207746 (US9265734, R26) Show SMILES Nc1ccccc1NC(=O)CCCCCNC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C21H23ClN4O2/c22-15-9-10-17-14(12-15)13-19(25-17)21(28)24-11-5-1-2-8-20(27)26-18-7-4-3-6-16(18)23/h3-4,6-7,9-10,12-13,25H,1-2,5,8,11,23H2,(H,24,28)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
BIOMARIN PHARMACEUTICAL INC. US Patent					Assay Description HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...				US Patent US9265734 (2016) BindingDB Entry DOI: 10.7270/Q2BK1B5B
					More data for this Ligand-Target Pair