BDBM207818 US9265734, R99

SMILES: Cc1ccc2[nH]nc(C(=O)NCCCCCC(=O)Nc3ccccc3N)c2c1

InChI Key: InChIKey=SPBQNVWFUUFQRU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM207818 (US9265734, R99) Show SMILES Cc1ccc2[nH]nc(C(=O)NCCCCCC(=O)Nc3ccccc3N)c2c1 Show InChI InChI=1S/C21H25N5O2/c1-14-10-11-17-15(13-14)20(26-25-17)21(28)23-12-6-2-3-9-19(27)24-18-8-5-4-7-16(18)22/h4-5,7-8,10-11,13H,2-3,6,9,12,22H2,1H3,(H,23,28)(H,24,27)(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
BIOMARIN PHARMACEUTICAL INC. US Patent					Assay Description HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...				US Patent US9265734 (2016) BindingDB Entry DOI: 10.7270/Q2BK1B5B
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM207818 (US9265734, R99) Show SMILES Cc1ccc2[nH]nc(C(=O)NCCCCCC(=O)Nc3ccccc3N)c2c1 Show InChI InChI=1S/C21H25N5O2/c1-14-10-11-17-15(13-14)20(26-25-17)21(28)23-12-6-2-3-9-19(27)24-18-8-5-4-7-16(18)22/h4-5,7-8,10-11,13H,2-3,6,9,12,22H2,1H3,(H,23,28)(H,24,27)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
BIOMARIN PHARMACEUTICAL INC. US Patent					Assay Description HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...				US Patent US9265734 (2016) BindingDB Entry DOI: 10.7270/Q2BK1B5B
					More data for this Ligand-Target Pair