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SMILES: Clc1ccc2[nH]cc(CCNC(=O)c3cccc(Cc4ccccc4)c3)c2c1

InChI Key: InChIKey=NRDVEWMCNQMVES-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207853   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-synuclein


(Homo sapiens (Human))		BDBM207853
PNG
(US9266832, Cpd010)
Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3cccc(Cc4ccccc4)c3)c2c1
Show InChI InChI=1S/C24H21ClN2O/c25-21-9-10-23-22(15-21)20(16-27-23)11-12-26-24(28)19-8-4-7-18(14-19)13-17-5-2-1-3-6-17/h1-10,14-16,27H,11-13H2,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 78n/an/an/an/a



Katholieke Universiteit Levun; K. U. Leuven R&D reMYND

US Patent


Assay Description
α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...

US Patent US9266832 (2016)


BindingDB Entry DOI: 10.7270/Q2319TP6
More data for this
Ligand-Target Pair