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SMILES: Clc1ccc2[nH]cc(CCNC(=O)c3ccc(Cn4ccnc4)cc3)c2c1

InChI Key: InChIKey=GKMWBNNSRYNGTC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207855   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-synuclein


(Homo sapiens (Human))		BDBM207855
PNG
(US9266832, Cpd012)
Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3ccc(Cn4ccnc4)cc3)c2c1
Show InChI InChI=1S/C21H19ClN4O/c22-18-5-6-20-19(11-18)17(12-25-20)7-8-24-21(27)16-3-1-15(2-4-16)13-26-10-9-23-14-26/h1-6,9-12,14,25H,7-8,13H2,(H,24,27)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 486n/an/an/an/a



Katholieke Universiteit Levun; K. U. Leuven R&D reMYND

US Patent


Assay Description
α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...

US Patent US9266832 (2016)


BindingDB Entry DOI: 10.7270/Q2319TP6
More data for this
Ligand-Target Pair