BindingDB logo
myBDB logout

null

SMILES: Clc1ccc2[nH]cc(CCNC(=O)c3cccc(CNCc4cccs4)c3)c2c1

InChI Key: InChIKey=LYMZFQATHXDJNX-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207865   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-synuclein


(Homo sapiens (Human))		BDBM207865
PNG
(US9266832, Cpd022)
Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3cccc(CNCc4cccs4)c3)c2c1
Show InChI InChI=1S/C23H22ClN3OS/c24-19-6-7-22-21(12-19)18(14-27-22)8-9-26-23(28)17-4-1-3-16(11-17)13-25-15-20-5-2-10-29-20/h1-7,10-12,14,25,27H,8-9,13,15H2,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 159n/an/an/an/a



Katholieke Universiteit Levun; K. U. Leuven R&D reMYND

US Patent


Assay Description
α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...

US Patent US9266832 (2016)


BindingDB Entry DOI: 10.7270/Q2319TP6
More data for this
Ligand-Target Pair