BDBM207881 US9266832, Cpd038

SMILES: Clc1ccc2[nH]cc(CCNC(=O)c3cccc(Cc4cccc(c4)C#N)c3)c2c1

InChI Key: InChIKey=PXQFFYZFKBCROQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207881 (US9266832, Cpd038) Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3cccc(Cc4cccc(c4)C#N)c3)c2c1 Show InChI InChI=1S/C25H20ClN3O/c26-22-7-8-24-23(14-22)21(16-29-24)9-10-28-25(30)20-6-2-4-18(13-20)11-17-3-1-5-19(12-17)15-27/h1-8,12-14,16,29H,9-11H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
					More data for this Ligand-Target Pair