BDBM207885 US9266832, Cpd042

SMILES: FC(F)(F)c1cccc(Cc2ccc(cc2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1

InChI Key: InChIKey=KRJIKDSERDFBJE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207885 (US9266832, Cpd042) Show SMILES FC(F)(F)c1cccc(Cc2ccc(cc2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1 Show InChI InChI=1S/C25H20ClF3N2O/c26-21-8-9-23-22(14-21)19(15-31-23)10-11-30-24(32)18-6-4-16(5-7-18)12-17-2-1-3-20(13-17)25(27,28)29/h1-9,13-15,31H,10-12H2,(H,30,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
					More data for this Ligand-Target Pair