BDBM207888 US9266832, Cpd045

SMILES: Clc1ccc(Cc2ccc(cc2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1

InChI Key: InChIKey=PTCJFPVGGBXZRA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207888 (US9266832, Cpd045) Show SMILES Clc1ccc(Cc2ccc(cc2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C24H20Cl2N2O/c25-20-7-3-17(4-8-20)13-16-1-5-18(6-2-16)24(29)27-12-11-19-15-28-23-10-9-21(26)14-22(19)23/h1-10,14-15,28H,11-13H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
					More data for this Ligand-Target Pair