BDBM207890 US9266832, Cpd047

SMILES: Clc1ccc2[nH]cc(CCNC(=O)c3ccc(Cc4ccccc4Cl)cc3)c2c1

InChI Key: InChIKey=CGELMXCEOZOWEK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207890 (US9266832, Cpd047) Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3ccc(Cc4ccccc4Cl)cc3)c2c1 Show InChI InChI=1S/C24H20Cl2N2O/c25-20-9-10-23-21(14-20)19(15-28-23)11-12-27-24(29)17-7-5-16(6-8-17)13-18-3-1-2-4-22(18)26/h1-10,14-15,28H,11-13H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
					More data for this Ligand-Target Pair