BDBM207897 US9266832, Cpd054

SMILES: Fc1ccccc1Cc1cccc(c1)C(=O)NCCc1c[nH]c2ccc(Cl)cc12

InChI Key: InChIKey=GHKIEFGDQSUEOC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207897 (US9266832, Cpd054) Show SMILES Fc1ccccc1Cc1cccc(c1)C(=O)NCCc1c[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C24H20ClFN2O/c25-20-8-9-23-21(14-20)19(15-28-23)10-11-27-24(29)18-6-3-4-16(13-18)12-17-5-1-2-7-22(17)26/h1-9,13-15,28H,10-12H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
					More data for this Ligand-Target Pair