BDBM207901 US9266832, Cpd058

SMILES: COc1cccc(Cc2cccc(c2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1

InChI Key: InChIKey=HKPLCQJMVFAYTF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207901 (US9266832, Cpd058) Show SMILES COc1cccc(Cc2cccc(c2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1 Show InChI InChI=1S/C25H23ClN2O2/c1-30-22-7-3-5-18(14-22)12-17-4-2-6-19(13-17)25(29)27-11-10-20-16-28-24-9-8-21(26)15-23(20)24/h2-9,13-16,28H,10-12H2,1H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	125	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
					More data for this Ligand-Target Pair