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SMILES: COc1cccc(Cc2cccc(c2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1F

InChI Key: InChIKey=NNWUXFOVIHIJLM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207909   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-synuclein


(Homo sapiens (Human))		BDBM207909
PNG
(US9266832, Cpd066)
Show SMILES COc1cccc(Cc2cccc(c2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1F
Show InChI InChI=1S/C25H22ClFN2O2/c1-31-23-7-3-5-17(24(23)27)12-16-4-2-6-18(13-16)25(30)28-11-10-19-15-29-22-9-8-20(26)14-21(19)22/h2-9,13-15,29H,10-12H2,1H3,(H,28,30)
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 386n/an/an/an/a



Katholieke Universiteit Levun; K. U. Leuven R&D reMYND

US Patent


Assay Description
α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...

US Patent US9266832 (2016)


BindingDB Entry DOI: 10.7270/Q2319TP6
More data for this
Ligand-Target Pair