BDBM208023 US9550778, chem-us-00180

SMILES: CCc1cccc(NC(=O)c2cc(cn3ncnc23)-c2cnccc2C)n1

InChI Key: InChIKey=FRIQEPBEIKCBFV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM208023 (US9550778, chem-us-00180) Show SMILES CCc1cccc(NC(=O)c2cc(cn3ncnc23)-c2cnccc2C)n1 Show InChI InChI=1S/C20H18N6O/c1-3-15-5-4-6-18(24-15)25-20(27)16-9-14(11-26-19(16)22-12-23-26)17-10-21-8-7-13(17)2/h4-12H,3H2,1-2H3,(H,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	7.4	25
Vanderbilt University US Patent					Assay Description The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...				US Patent US9550778 (2017) BindingDB Entry DOI: 10.7270/Q24M96J4
					More data for this Ligand-Target Pair