BDBM208457 US9266869, 15

SMILES: Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(=O)(CCCO)CCCO

InChI Key: InChIKey=WZZOTDRFRPWXSI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 208457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM208457 (US9266869, 15) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(=O)(CCCO)CCCO Show InChI InChI=1S/C26H28N4O6S/c1-18-9-12-36-23(18)26(34)29-22-6-2-5-19(15-22)7-8-20-16-21(17-28-24(20)27)25(33)30-37(35,13-3-10-31)14-4-11-32/h2,5-6,9,12,15-17,31-32H,3-4,10-11,13-14H2,1H3,(H2,27,28)(H,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208457 (US9266869, 15) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(=O)(CCCO)CCCO Show InChI InChI=1S/C26H28N4O6S/c1-18-9-12-36-23(18)26(34)29-22-6-2-5-19(15-22)7-8-20-16-21(17-28-24(20)27)25(33)30-37(35,13-3-10-31)14-4-11-32/h2,5-6,9,12,15-17,31-32H,3-4,10-11,13-14H2,1H3,(H2,27,28)(H,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair