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SMILES: COc1cccc(c1)C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(=O)(CCCO)CCCO

InChI Key: InChIKey=FHSJWUWRONWZTJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208463   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM208463
PNG
(US9266869, 21)
Show SMILES COc1cccc(c1)C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(=O)(CCCO)CCCO
Show InChI InChI=1S/C28H30N4O6S/c1-38-25-9-3-7-22(18-25)27(35)31-24-8-2-6-20(16-24)10-11-21-17-23(19-30-26(21)29)28(36)32-39(37,14-4-12-33)15-5-13-34/h2-3,6-9,16-19,33-34H,4-5,12-15H2,1H3,(H2,29,30)(H,31,35)
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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/a7.430



Allergan, Inc.

US Patent


Assay Description
Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...

US Patent US9266869 (2016)


BindingDB Entry DOI: 10.7270/Q2NV9H33
More data for this
Ligand-Target Pair