BDBM208525 US9266870, 41

SMILES: Cc1ccc(c(c1)C(=O)N1CCCOC1Cn1ccc(n1)-c1ccc(F)cc1)-c1ncccn1

InChI Key: InChIKey=LRBYYJMSSHIJKG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 208525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM208525 (US9266870, 41) Show SMILES Cc1ccc(c(c1)C(=O)N1CCCOC1Cn1ccc(n1)-c1ccc(F)cc1)-c1ncccn1 Show InChI InChI=1S/C26H24FN5O2/c1-18-4-9-21(25-28-11-2-12-29-25)22(16-18)26(33)32-13-3-15-34-24(32)17-31-14-10-23(30-31)19-5-7-20(27)8-6-19/h2,4-12,14,16,24H,3,13,15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	37
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...				US Patent US9266870 (2016) BindingDB Entry DOI: 10.7270/Q2J38RCP
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM208525 (US9266870, 41) Show SMILES Cc1ccc(c(c1)C(=O)N1CCCOC1Cn1ccc(n1)-c1ccc(F)cc1)-c1ncccn1 Show InChI InChI=1S/C26H24FN5O2/c1-18-4-9-21(25-28-11-2-12-29-25)22(16-18)26(33)32-13-3-15-34-24(32)17-31-14-10-23(30-31)19-5-7-20(27)8-6-19/h2,4-12,14,16,24H,3,13,15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	37
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...				US Patent US9266870 (2016) BindingDB Entry DOI: 10.7270/Q2J38RCP
					More data for this Ligand-Target Pair