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SMILES: Cc1ccc(c(c1)C(=O)N1CCOC1Cc1ccn(n1)-c1ccc(F)cn1)-n1nccn1

InChI Key: InChIKey=CWBJXWWFPDALKJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 208529   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM208529 (US9266870, 45) Show SMILES Cc1ccc(c(c1)C(=O)N1CCOC1Cc1ccn(n1)-c1ccc(F)cn1)-n1nccn1 Show InChI InChI=1S/C22H20FN7O2/c1-15-2-4-19(30-25-7-8-26-30)18(12-15)22(31)28-10-11-32-21(28)13-17-6-9-29(27-17)20-5-3-16(23)14-24-20/h2-9,12,14,21H,10-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.1	n/a	n/a	n/a	n/a	7.4	37
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...				US Patent US9266870 (2016) BindingDB Entry DOI: 10.7270/Q2J38RCP
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM208529 (US9266870, 45) Show SMILES Cc1ccc(c(c1)C(=O)N1CCOC1Cc1ccn(n1)-c1ccc(F)cn1)-n1nccn1 Show InChI InChI=1S/C22H20FN7O2/c1-15-2-4-19(30-25-7-8-26-30)18(12-15)22(31)28-10-11-32-21(28)13-17-6-9-29(27-17)20-5-3-16(23)14-24-20/h2-9,12,14,21H,10-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.4	37
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...				US Patent US9266870 (2016) BindingDB Entry DOI: 10.7270/Q2J38RCP
					More data for this Ligand-Target Pair