Found 4 hits for monomerid = 209303 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Fibroblast growth factor receptor 4 [388-802]
(Homo sapiens (Human)) | BDBM209303
(US9266883, 61)Show SMILES COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N Show InChI InChI=1S/C20H18F3N5O4/c1-31-5-6-32-16-8-17(25-10-13(16)9-24)27-19(30)28-4-2-3-12-7-14(20(21,22)23)15(11-29)26-18(12)28/h7-8,10-11H,2-6H2,1H3,(H,25,27,30) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG
US Patent
| Assay Description
Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an... |
US Patent US9266883 (2016)
BindingDB Entry DOI: 10.7270/Q2CC0ZGP |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 4
(Homo sapiens (Human)) | BDBM209303
(US9266883, 61)Show SMILES COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N Show InChI InChI=1S/C20H18F3N5O4/c1-31-5-6-32-16-8-17(25-10-13(16)9-24)27-19(30)28-4-2-3-12-7-14(20(21,22)23)15(11-29)26-18(12)28/h7-8,10-11H,2-6H2,1H3,(H,25,27,30) | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 4
(Mus musculus) | BDBM209303
(US9266883, 61)Show SMILES COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N Show InChI InChI=1S/C20H18F3N5O4/c1-31-5-6-32-16-8-17(25-10-13(16)9-24)27-19(30)28-4-2-3-12-7-14(20(21,22)23)15(11-29)26-18(12)28/h7-8,10-11H,2-6H2,1H3,(H,25,27,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 4
(Mus musculus) | BDBM209303
(US9266883, 61)Show SMILES COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N Show InChI InChI=1S/C20H18F3N5O4/c1-31-5-6-32-16-8-17(25-10-13(16)9-24)27-19(30)28-4-2-3-12-7-14(20(21,22)23)15(11-29)26-18(12)28/h7-8,10-11H,2-6H2,1H3,(H,25,27,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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