BDBM209352 US9266883, 161

SMILES: CN1CCOC(CNc2cc(NC(=O)N3CCCc4cc(C(F)F)c(C=O)nc34)ncc2C#N)C1

InChI Key: InChIKey=WXHUVNMFRYCSGQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (FGFR4) (Homo sapiens (Human))	BDBM209352 (US9266883, 161) Show SMILES CN1CCOC(CNc2cc(NC(=O)N3CCCc4cc(C(F)F)c(C=O)nc34)ncc2C#N)C1 Show InChI InChI=1S/C23H25F2N7O3/c1-31-5-6-35-16(12-31)11-27-18-8-20(28-10-15(18)9-26)30-23(34)32-4-2-3-14-7-17(21(24)25)19(13-33)29-22(14)32/h7-8,10,13,16,21H,2-6,11-12H2,1H3,(H2,27,28,30,34)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair