BDBM210839 US9290467, 9

SMILES: Clc1cc2C[C@H](NC(=O)c3cc(Br)ccc3OCCCCOc1cc2)C(=O)NC1(CC1)C#N

InChI Key: InChIKey=LMRCXYZQJOJAAM-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 210839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM210839 (US9290467, 9) Show SMILES Clc1cc2C[C@H](NC(=O)c3cc(Br)ccc3OCCCCOc1cc2)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H23BrClN3O4/c25-16-4-6-20-17(13-16)22(30)28-19(23(31)29-24(14-27)7-8-24)12-15-3-5-21(18(26)11-15)33-10-2-1-9-32-20/h3-6,11,13,19H,1-2,7-10,12H2,(H,28,30)(H,29,31)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	6.5	n/a
HOFFMANN—LA ROCHE INC. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US9290467 (2016) BindingDB Entry DOI: 10.7270/Q2H130VZ
					More data for this Ligand-Target Pair