null

SMILES: FC(F)(F)c1cccc(c1)N1C2=C([C@H](N(C(=O)NC3CS(=O)(=O)C3)C1=O)c1ccc(cc1)C#N)C(=O)CC2

InChI Key: InChIKey=SDBSCZKUJXFACU-JOCHJYFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 211885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM211885 (US9290459, 45.6 | US9670166, 45.6) Show SMILES FC(F)(F)c1cccc(c1)N1C2=C([C@H](N(C(=O)NC3CS(=O)(=O)C3)C1=O)c1ccc(cc1)C#N)C(=O)CC2 |r,c:12| Show InChI InChI=1S/C25H19F3N4O5S/c26-25(27,28)16-2-1-3-18(10-16)31-19-8-9-20(33)21(19)22(15-6-4-14(11-29)5-7-15)32(24(31)35)23(34)30-17-12-38(36,37)13-17/h1-7,10,17,22H,8-9,12-13H2,(H,30,34)/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...				US Patent US9670166 (2017) BindingDB Entry DOI: 10.7270/Q25Q4T8F
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM211885 (US9290459, 45.6 | US9670166, 45.6) Show SMILES FC(F)(F)c1cccc(c1)N1C2=C([C@H](N(C(=O)NC3CS(=O)(=O)C3)C1=O)c1ccc(cc1)C#N)C(=O)CC2 |r,c:12| Show InChI InChI=1S/C25H19F3N4O5S/c26-25(27,28)16-2-1-3-18(10-16)31-19-8-9-20(33)21(19)22(15-6-4-14(11-29)5-7-15)32(24(31)35)23(34)30-17-12-38(36,37)13-17/h1-7,10,17,22H,8-9,12-13H2,(H,30,34)/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...				US Patent US9290459 (2016) BindingDB Entry DOI: 10.7270/Q2KS6QD5
					More data for this Ligand-Target Pair