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SMILES: Cn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cnc3C(O)=O)cccc12

InChI Key: InChIKey=RGLOJSWQWWYRGN-DZGCQCFKSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 211959   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK [2-635]


(Homo sapiens (Human))		BDBM211959
PNG
(US9290481, 3.1)
Show SMILES Cn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cnc3C(O)=O)cccc12 |r|
Show InChI InChI=1S/C20H24N6O2/c1-26-10-9-12-14(7-4-8-16(12)26)24-19-18(20(27)28)22-11-17(25-19)23-15-6-3-2-5-13(15)21/h4,7-11,13,15H,2-3,5-6,21H2,1H3,(H,27,28)(H2,23,24,25)/t13-,15+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.5n/an/an/an/a7.530



NOVARTIS AG

US Patent


Assay Description
All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...

US Patent US9290481 (2016)


BindingDB Entry DOI: 10.7270/Q2G15ZPR
More data for this
Ligand-Target Pair