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SMILES: Cc1nc(N)cc(OCC(=O)C(C)(C)C)c1CNC(=O)c1cnn(Cc2ccc3ccccc3c2)c1

InChI Key: InChIKey=QXVKLXZLQIBRSP-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212117   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasma kallikrein


(Homo sapiens (Human))		BDBM212117
PNG
(US9290485, 149)
Show SMILES Cc1nc(N)cc(OCC(=O)C(C)(C)C)c1CNC(=O)c1cnn(Cc2ccc3ccccc3c2)c1
Show InChI InChI=1S/C28H31N5O3/c1-18-23(24(12-26(29)32-18)36-17-25(34)28(2,3)4)14-30-27(35)22-13-31-33(16-22)15-19-9-10-20-7-5-6-8-21(20)11-19/h5-13,16H,14-15,17H2,1-4H3,(H2,29,32)(H,30,35)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.80n/an/an/an/a7.825



NOVARTIS AG

US Patent


Assay Description
Enzymatic reactions were conducted in â¿¿assay bufferâ¿¿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...

US Patent US9290485 (2016)


BindingDB Entry DOI: 10.7270/Q26H4G73
More data for this
Ligand-Target Pair