null
SMILES: CN[C@H](C)C(=O)Nc1cc(cc(n1)C#Cc1ccc2c(C)nccc2c1)-c1nc(C)nc2c(C)nn(C)c12
InChI Key: InChIKey=FWARKFCRMQWMOT-GOSISDBHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Baculoviral IAP repeat-containing protein 2 [256-363] (Homo sapiens (Human)) | BDBM213381 (US9278978, 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH US Patent | Assay Description BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% TritonX100) for one... | US Patent US9278978 (2016) BindingDB Entry DOI: 10.7270/Q2JM28G4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human)) | BDBM213381 (US9278978, 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH US Patent | Assay Description BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% TritonX100) for one... | US Patent US9278978 (2016) BindingDB Entry DOI: 10.7270/Q2JM28G4 | |||||||||||
More data for this Ligand-Target Pair |