BDBM21352 2-{1-[(3,4-dichlorobenzene)sulfonyl]-1H-indol-3-yl}ethan-1-amine::Substituted phenylsulfonyltryptamine, 11k

SMILES: NCCc1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=DCLULEWKNCWYMQ-UHFFFAOYSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM21352 (2-{1-[(3,4-dichlorobenzene)sulfonyl]-1H-indol-3-yl...) Show SMILES NCCc1cn(c2ccccc12)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H14Cl2N2O2S/c17-14-6-5-12(9-15(14)18)23(21,22)20-10-11(7-8-19)13-3-1-2-4-16(13)20/h1-6,9-10H,7-8,19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	30	-10.2	n/a	n/a	n/a	n/a	n/a	7.4	22
Wyeth Research					Assay Description IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...				J Med Chem 50: 5535-8 (2007) Article DOI: 10.1021/jm070521y BindingDB Entry DOI: 10.7270/Q23R0R5G
					More data for this Ligand-Target Pair