BDBM214713 US9296747, Example 8

SMILES: Cn1nccc1Nc1ncc2CN(CCc2n1)C(=O)c1cccnc1

InChI Key: InChIKey=HTDUCXSZMDZCEV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 214713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214713 (US9296747, Example 8) Show SMILES Cn1nccc1Nc1ncc2CN(CCc2n1)C(=O)c1cccnc1 Show InChI InChI=1S/C17H17N7O/c1-23-15(4-7-20-23)22-17-19-10-13-11-24(8-5-14(13)21-17)16(25)12-3-2-6-18-9-12/h2-4,6-7,9-10H,5,8,11H2,1H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214713 (US9296747, Example 8) Show SMILES Cn1nccc1Nc1ncc2CN(CCc2n1)C(=O)c1cccnc1 Show InChI InChI=1S/C17H17N7O/c1-23-15(4-7-20-23)22-17-19-10-13-11-24(8-5-14(13)21-17)16(25)12-3-2-6-18-9-12/h2-4,6-7,9-10H,5,8,11H2,1H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair