BDBM214714 US9296747, Example 9

SMILES: O=C(N1CCc2nc(Nc3ccsc3)ncc2C1)c1cccnc1

InChI Key: InChIKey=ZPDYDVHXPRUTID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214714 (US9296747, Example 9) Show SMILES O=C(N1CCc2nc(Nc3ccsc3)ncc2C1)c1cccnc1 Show InChI InChI=1S/C17H15N5OS/c23-16(12-2-1-5-18-8-12)22-6-3-15-13(10-22)9-19-17(21-15)20-14-4-7-24-11-14/h1-2,4-5,7-9,11H,3,6,10H2,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair