BDBM215749 US9296748, II-36

SMILES: CC(c1ccccn1)n1c(nc2cnc(Cl)cc12)-c1cc(C)c(=O)n(C)c1

InChI Key: InChIKey=QIIFKSKSJOZOKF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 215749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (BRD4) (aa 44-168) (Homo sapiens (Human))	BDBM215749 (US9296748, II-36) Show SMILES CC(c1ccccn1)n1c(nc2cnc(Cl)cc12)-c1cc(C)c(=O)n(C)c1 Show InChI InChI=1S/C20H18ClN5O/c1-12-8-14(11-25(3)20(12)27)19-24-16-10-23-18(21)9-17(16)26(19)13(2)15-6-4-5-7-22-15/h4-11,13H,1-3H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...				US Patent US9296748 (2016) BindingDB Entry DOI: 10.7270/Q21G0K4K
					More data for this Ligand-Target Pair