BindingDB logo
myBDB logout

null

SMILES: Cc1cc(cn(C)c1=O)-c1nc2ncccc2n1Cc1ccccc1

InChI Key: InChIKey=BYEYSMKJKUCVJE-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 215769   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-168]


(Homo sapiens (Human))		BDBM215769
PNG
(US9296748, IV-1)
Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ncccc2n1Cc1ccccc1
Show InChI InChI=1S/C20H18N4O/c1-14-11-16(13-23(2)20(14)25)19-22-18-17(9-6-10-21-18)24(19)12-15-7-4-3-5-8-15/h3-11,13H,12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 313n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...

US Patent US9296748 (2016)


BindingDB Entry DOI: 10.7270/Q21G0K4K
More data for this
Ligand-Target Pair