BDBM21694 1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one::1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one::Benzimidazolone, 3

SMILES: COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key: InChIKey=MWZDWGQFJGABMO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM21694 (1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...) Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C22H22N4O3/c1-29-16-6-7-17-14(12-16)13-19(23-17)21(27)25-10-8-15(9-11-25)26-20-5-3-2-4-18(20)24-22(26)28/h2-7,12-13,15,23H,8-11H2,1H3,(H,24,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.39E+3	n/a	n/a	7.2	37
Amgen					Assay Description hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...				Bioorg Med Chem Lett 17: 6633-7 (2007) Article DOI: 10.1016/j.bmcl.2007.09.043 BindingDB Entry DOI: 10.7270/Q25H7DJ4
					More data for this Ligand-Target Pair