null

SMILES: FC(F)(F)C1(CC1)C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1

InChI Key: InChIKey=BXFLCLIUJGTFTB-ZROIWOOFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220027 (US9303033, W46, Table 57A, Compound 3) Show SMILES FC(F)(F)C1(CC1)C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C22H23F3N8O3/c23-22(24,25)21(3-4-21)19(35)32-7-5-31(6-8-32)15-10-16(27-13-1-2-13)33-17(29-15)12(11-26-33)9-14-18(34)30-20(36)28-14/h9-11,13,27H,1-8H2,(H2,28,30,34,36)/b14-9-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220027 (US9303033, W46, Table 57A, Compound 3) Show SMILES FC(F)(F)C1(CC1)C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C22H23F3N8O3/c23-22(24,25)21(3-4-21)19(35)32-7-5-31(6-8-32)15-10-16(27-13-1-2-13)33-17(29-15)12(11-26-33)9-14-18(34)30-20(36)28-14/h9-11,13,27H,1-8H2,(H2,28,30,34,36)/b14-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.04E+4	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair