null

SMILES: FC1(F)CC1C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1

InChI Key: InChIKey=XLDPATMKVYWXOK-AUWJEWJLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220032 (US9303033, B47, Table 57A, Compound 8) Show SMILES FC1(F)CC1C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H22F2N8O3/c22-21(23)9-13(21)19(33)30-5-3-29(4-6-30)15-8-16(25-12-1-2-12)31-17(27-15)11(10-24-31)7-14-18(32)28-20(34)26-14/h7-8,10,12-13,25H,1-6,9H2,(H2,26,28,32,34)/b14-7-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220032 (US9303033, B47, Table 57A, Compound 8) Show SMILES FC1(F)CC1C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H22F2N8O3/c22-21(23)9-13(21)19(33)30-5-3-29(4-6-30)15-8-16(25-12-1-2-12)31-17(27-15)11(10-24-31)7-14-18(32)28-20(34)26-14/h7-8,10,12-13,25H,1-6,9H2,(H2,26,28,32,34)/b14-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair