BDBM220059 US9303033, C48, Table 58A, Compound 26::US9303033, I49, Table 59A, Compound 19

SMILES: Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/NC(=O)NC3=O)cnn12

InChI Key: InChIKey=LGEPKJARNKBUNX-JYOAFUTRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 220059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit beta (CK2 beta) (Homo sapiens (Human))	BDBM220059 (US9303033, C48, Table 58A, Compound 26 | US9303033...) Show SMILES Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/NC(=O)NC3=O)cnn12 Show InChI InChI=1S/C16H11ClFN7O2/c17-8-1-2-9(18)10(4-8)21-13-5-12(19)25-14(23-13)7(6-20-25)3-11-15(26)24-16(27)22-11/h1-6H,19H2,(H,21,23)(H2,22,24,26,27)/b11-3-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.08E+4	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220059 (US9303033, C48, Table 58A, Compound 26 | US9303033...) Show SMILES Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/NC(=O)NC3=O)cnn12 Show InChI InChI=1S/C16H11ClFN7O2/c17-8-1-2-9(18)10(4-8)21-13-5-12(19)25-14(23-13)7(6-20-25)3-11-15(26)24-16(27)22-11/h1-6H,19H2,(H,21,23)(H2,22,24,26,27)/b11-3-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220059 (US9303033, C48, Table 58A, Compound 26 | US9303033...) Show SMILES Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/NC(=O)NC3=O)cnn12 Show InChI InChI=1S/C16H11ClFN7O2/c17-8-1-2-9(18)10(4-8)21-13-5-12(19)25-14(23-13)7(6-20-25)3-11-15(26)24-16(27)22-11/h1-6H,19H2,(H,21,23)(H2,22,24,26,27)/b11-3-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair