null

SMILES: C[C@H](Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(Cl)ccc1F

InChI Key: InChIKey=NJJIFTBJMGOWPK-KCUAXXGYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220062 (US9303033, F48, Table 58A, Compound 29) Show SMILES C[C@H](Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C21H19ClFN7O2/c1-10(14-7-12(22)2-5-15(14)23)25-17-8-18(26-13-3-4-13)30-19(28-17)11(9-24-30)6-16-20(31)29-21(32)27-16/h2,5-10,13,26H,3-4H2,1H3,(H,25,28)(H2,27,29,31,32)/b16-6-/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220062 (US9303033, F48, Table 58A, Compound 29) Show SMILES C[C@H](Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C21H19ClFN7O2/c1-10(14-7-12(22)2-5-15(14)23)25-17-8-18(26-13-3-4-13)30-19(28-17)11(9-24-30)6-16-20(31)29-21(32)27-16/h2,5-10,13,26H,3-4H2,1H3,(H,25,28)(H2,27,29,31,32)/b16-6-/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair