null

SMILES: Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/CC(=O)NC3=O)cnn12

InChI Key: InChIKey=JQZXCMCTEKIIGS-FPYGCLRLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220065 (US9303033, I48, Table 58A, Compound 32) Show SMILES Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/CC(=O)NC3=O)cnn12 Show InChI InChI=1S/C17H12ClFN6O2/c18-10-1-2-11(19)12(5-10)22-14-6-13(20)25-16(23-14)9(7-21-25)3-8-4-15(26)24-17(8)27/h1-3,5-7H,4,20H2,(H,22,23)(H,24,26,27)/b8-3+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220065 (US9303033, I48, Table 58A, Compound 32) Show SMILES Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/CC(=O)NC3=O)cnn12 Show InChI InChI=1S/C17H12ClFN6O2/c18-10-1-2-11(19)12(5-10)22-14-6-13(20)25-16(23-14)9(7-21-25)3-8-4-15(26)24-17(8)27/h1-3,5-7H,4,20H2,(H,22,23)(H,24,26,27)/b8-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.69E+3	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair