null

SMILES: FC(F)(F)c1cccc(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1

InChI Key: InChIKey=ATFBLRRPYUJUSX-AUWJEWJLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220068 (US9303033, L48, Table 58A, Compound 35) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H16F3N7O3/c22-21(23,24)12-3-1-2-10(6-12)18(32)29-15-8-16(26-13-4-5-13)31-17(28-15)11(9-25-31)7-14-19(33)30-20(34)27-14/h1-3,6-9,13,26H,4-5H2,(H,28,29,32)(H2,27,30,33,34)/b14-7-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220068 (US9303033, L48, Table 58A, Compound 35) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H16F3N7O3/c22-21(23,24)12-3-1-2-10(6-12)18(32)29-15-8-16(26-13-4-5-13)31-17(28-15)11(9-25-31)7-14-19(33)30-20(34)27-14/h1-3,6-9,13,26H,4-5H2,(H,28,29,32)(H2,27,30,33,34)/b14-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair