null

SMILES: Fc1cc(F)c(F)c(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1

InChI Key: InChIKey=SRBCHFWLSVRQIB-DXNYSGJVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220070 (US9303033, N48, Table 58A, Compound 37) Show SMILES Fc1cc(F)c(F)c(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C20H14F3N7O3/c21-9-4-11(16(23)12(22)5-9)18(31)28-14-6-15(25-10-1-2-10)30-17(27-14)8(7-24-30)3-13-19(32)29-20(33)26-13/h3-7,10,25H,1-2H2,(H,27,28,31)(H2,26,29,32,33)/b13-3-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220070 (US9303033, N48, Table 58A, Compound 37) Show SMILES Fc1cc(F)c(F)c(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C20H14F3N7O3/c21-9-4-11(16(23)12(22)5-9)18(31)28-14-6-15(25-10-1-2-10)30-17(27-14)8(7-24-30)3-13-19(32)29-20(33)26-13/h3-7,10,25H,1-2H2,(H,27,28,31)(H2,26,29,32,33)/b13-3-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair