null

SMILES: CC12C[C@@H]3C[C@H]1C[C@H]2C[C@@H](C3)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(N2CCC[C@H]2C(O)=O)c1=O

InChI Key: InChIKey=TWOHYSGFUMRTOK-DJXZHOHSSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 220392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human))	BDBM220392 (US9290488, CC02) Show SMILES CC12C[C@@H]3C[C@H]1C[C@H]2C[C@@H](C3)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(N2CCC[C@H]2C(O)=O)c1=O |r,THB:9:11:18.19.17:13.15.14| Show InChI InChI=1S/C32H42N4O3/c1-32-18-19-12-20(32)14-21(32)15-24(13-19)35-22-6-4-7-23(35)17-25(16-22)36-27-9-3-2-8-26(27)33-29(30(36)37)34-11-5-10-28(34)31(38)39/h2-3,8-9,19-25,28H,4-7,10-18H2,1H3,(H,38,39)/t19-,20+,21+,22-,23+,24-,25+,28+,32?/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15	-10.7	n/a	n/a	n/a	n/a	n/a	7.4	25
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in a ...				US Patent US9290488 (2016) BindingDB Entry DOI: 10.7270/Q2GF0SCW
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM220392 (US9290488, CC02) Show SMILES CC12C[C@@H]3C[C@H]1C[C@H]2C[C@@H](C3)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(N2CCC[C@H]2C(O)=O)c1=O |r,THB:9:11:18.19.17:13.15.14| Show InChI InChI=1S/C32H42N4O3/c1-32-18-19-12-20(32)14-21(32)15-24(13-19)35-22-6-4-7-23(35)17-25(16-22)36-27-9-3-2-8-26(27)33-29(30(36)37)34-11-5-10-28(34)31(38)39/h2-3,8-9,19-25,28H,4-7,10-18H2,1H3,(H,38,39)/t19-,20+,21+,22-,23+,24-,25+,28+,32?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	51	-9.94	n/a	n/a	n/a	n/a	n/a	7.4	25
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose displacement assays used 0.4-0.8 nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 μg membrane protein (recombinant kappa opioid rece...				US Patent US9290488 (2016) BindingDB Entry DOI: 10.7270/Q2GF0SCW
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM220392 (US9290488, CC02) Show SMILES CC12C[C@@H]3C[C@H]1C[C@H]2C[C@@H](C3)N1[C@H]2CCC[C@@H]1C[C@@H](C2)n1c2ccccc2nc(N2CCC[C@H]2C(O)=O)c1=O |r,THB:9:11:18.19.17:13.15.14| Show InChI InChI=1S/C32H42N4O3/c1-32-18-19-12-20(32)14-21(32)15-24(13-19)35-22-6-4-7-23(35)17-25(16-22)36-27-9-3-2-8-26(27)33-29(30(36)37)34-11-5-10-28(34)31(38)39/h2-3,8-9,19-25,28H,4-7,10-18H2,1H3,(H,38,39)/t19-,20+,21+,22-,23+,24-,25+,28+,32?/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	86	-9.63	n/a	n/a	n/a	n/a	n/a	7.4	25
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-receptors (Perkin Elmer, Shelton, Conn.). Radioligand ...				US Patent US9290488 (2016) BindingDB Entry DOI: 10.7270/Q2GF0SCW
					More data for this Ligand-Target Pair