BDBM221329 US9303023, 28

SMILES: COc1ccc(cc1)-c1ocnc1C(=O)Nc1cnn(CCc2c[nH]c3ccc(OC)cc23)c1

InChI Key: InChIKey=SDRHSQUSJLGBLJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM221329 (US9303023, 28) Show SMILES COc1ccc(cc1)-c1ocnc1C(=O)Nc1cnn(CCc2c[nH]c3ccc(OC)cc23)c1 Show InChI InChI=1S/C25H23N5O4/c1-32-19-5-3-16(4-6-19)24-23(27-15-34-24)25(31)29-18-13-28-30(14-18)10-9-17-12-26-22-8-7-20(33-2)11-21(17)22/h3-8,11-15,26H,9-10H2,1-2H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9303023 (2016) BindingDB Entry DOI: 10.7270/Q2251H10
					More data for this Ligand-Target Pair