BDBM221371 US9303023, 68

SMILES: CCOc1cc(OC)nc(CCCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)n1

InChI Key: InChIKey=BNBOEZSHJCDQQW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM221371 (US9303023, 68) Show SMILES CCOc1cc(OC)nc(CCCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)n1 Show InChI InChI=1S/C24H26N6O4/c1-4-33-21-12-20(32-3)28-19(29-21)9-6-10-30-14-18(13-26-30)27-24(31)22-23(34-15-25-22)17-8-5-7-16(2)11-17/h5,7-8,11-15H,4,6,9-10H2,1-3H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9303023 (2016) BindingDB Entry DOI: 10.7270/Q2251H10
					More data for this Ligand-Target Pair