BDBM221413 US9303023, 110
SMILES: COc1cc(OC)nc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)n1
InChI Key: InChIKey=LPVGXTRSJBXLPM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM221413 (US9303023, 110) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | 37 |
ACTELION PHARMACEUTICALS LTD. US Patent | Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (... | US Patent US9303023 (2016) BindingDB Entry DOI: 10.7270/Q2251H10 | |||||||||||
More data for this Ligand-Target Pair |