BDBM22193 1-{4-[2-(diphenylmethoxy)ethyl]piperazin-1-yl}-2-methyl-3-phenylpropan-2-ol::GBR 12935 Analogue, 22

SMILES: CC(O)(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1

InChI Key: InChIKey=JUOTXFDGIKRFRE-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22193 (1-{4-[2-(diphenylmethoxy)ethyl]piperazin-1-yl}-2-m...) Show SMILES CC(O)(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C29H36N2O2/c1-29(32,23-25-11-5-2-6-12-25)24-31-19-17-30(18-20-31)21-22-33-28(26-13-7-3-8-14-26)27-15-9-4-10-16-27/h2-16,28,32H,17-24H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...				J Med Chem 51: 2795-806 (2008) Article DOI: 10.1021/jm701270n BindingDB Entry DOI: 10.7270/Q2B27SK6
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM22193 (1-{4-[2-(diphenylmethoxy)ethyl]piperazin-1-yl}-2-m...) Show SMILES CC(O)(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C29H36N2O2/c1-29(32,23-25-11-5-2-6-12-25)24-31-19-17-30(18-20-31)21-22-33-28(26-13-7-3-8-14-26)27-15-9-4-10-16-27/h2-16,28,32H,17-24H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...				J Med Chem 51: 2795-806 (2008) Article DOI: 10.1021/jm701270n BindingDB Entry DOI: 10.7270/Q2B27SK6
					More data for this Ligand-Target Pair