BDBM2221 US8507676, 80

SMILES: C\C(=N/O)c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1

InChI Key: InChIKey=KBNLPJURVZJDPS-SSDVNMTOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM2221 (US8507676, 80) Show SMILES C\C(=N/O)c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C17H14N6O/c1-11(22-24)14-6-7-16-19-20-17(23(16)21-14)10-12-4-5-15-13(9-12)3-2-8-18-15/h2-9,24H,10H2,1H3/b22-11+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair