BDBM222260 (Z)-4-(2-((E)-4-(3-methoxyphenyl)-1-morpholino-2-oxobut-3-enylidene)hydrazinyl) benzenesulfonamide (4c)
SMILES: COc1cccc(\C=C\C(=O)C(=N\Nc2ccc(cc2)S(N)(=O)=O)\N2CCOCC2)c1
InChI Key: InChIKey=BQVHMEFCHBALGW-MGNOWFFUSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Intestinal alkaline phosphatase (IAP) (Bos taurus (Cattle)) | BDBM222260 ((Z)-4-(2-((E)-4-(3-methoxyphenyl)-1-morpholino-2-o...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair |