BDBM22271 4-butyl-N-[2-(1H-indol-3-yl)ethyl]benzene-1-sulfonamide::tryptamine sulfonamide, 9

SMILES: CCCCc1ccc(cc1)S(=O)(=O)NCCc1c[nH]c2ccccc12

InChI Key: InChIKey=ZDWCCCTVMQMVQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM22271 (4-butyl-N-[2-(1H-indol-3-yl)ethyl]benzene-1-sulfon...) Show SMILES CCCCc1ccc(cc1)S(=O)(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C20H24N2O2S/c1-2-3-6-16-9-11-18(12-10-16)25(23,24)22-14-13-17-15-21-20-8-5-4-7-19(17)20/h4-5,7-12,15,21-22H,2-3,6,13-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...				Bioorg Med Chem Lett 15: 1435-40 (2005) Article DOI: 10.1016/j.bmcl.2004.12.081 BindingDB Entry DOI: 10.7270/Q2T43RD2
					More data for this Ligand-Target Pair