BDBM22277 N-[2-(1H-indol-3-yl)ethyl]-4-[4-(propan-2-yl)phenyl]benzene-1-sulfonamide::tryptamine sulfonamide, 16

SMILES: CC(C)c1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCCc1c[nH]c2ccccc12

InChI Key: InChIKey=XIQQZRCWOSRXEN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM22277 (N-[2-(1H-indol-3-yl)ethyl]-4-[4-(propan-2-yl)pheny...) Show SMILES CC(C)c1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C25H26N2O2S/c1-18(2)19-7-9-20(10-8-19)21-11-13-23(14-12-21)30(28,29)27-16-15-22-17-26-25-6-4-3-5-24(22)25/h3-14,17-18,26-27H,15-16H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...				Bioorg Med Chem Lett 15: 1435-40 (2005) Article DOI: 10.1016/j.bmcl.2004.12.081 BindingDB Entry DOI: 10.7270/Q2T43RD2
					More data for this Ligand-Target Pair