BDBM22282 N-[2-(1H-indol-3-yl)ethyl]-N-methyl-4-pentylbenzene-1-sulfonamide::tryptamine sulfonamide, 22

SMILES: CCCCCc1ccc(cc1)S(=O)(=O)N(C)CCc1c[nH]c2ccccc12

InChI Key: InChIKey=ZWSBMFNHGYPHHE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM22282 (N-[2-(1H-indol-3-yl)ethyl]-N-methyl-4-pentylbenzen...) Show SMILES CCCCCc1ccc(cc1)S(=O)(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C22H28N2O2S/c1-3-4-5-8-18-11-13-20(14-12-18)27(25,26)24(2)16-15-19-17-23-22-10-7-6-9-21(19)22/h6-7,9-14,17,23H,3-5,8,15-16H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...				Bioorg Med Chem Lett 15: 1435-40 (2005) Article DOI: 10.1016/j.bmcl.2004.12.081 BindingDB Entry DOI: 10.7270/Q2T43RD2
					More data for this Ligand-Target Pair